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a Transplant Unit, Harefield Hospital, Harefield,
Middlesex UB9 6JH, UK, b Royal Brompton
Hospital, Sydney Street, London SW3 6NP, UK, c National Heart and Lung Institute of Imperial College of
Science Technology and Medicine, University of London, Dovehouse
Street, London SW3 6LY, UK
Correspondence to: Dr M Burke, Department of Pathology, Harefield Hospital, Middlesex UB9 6JH, UK.
Received 23 July 1997; Returned to authors 16 October 1997; Revised version received 4 November 1997; Accepted for publication 20 November 1997
Langerhans' cell histiocytosis may cause irreversible
respiratory failure due to progressive destruction of lung parenchyma and widespread cystic change. Transplantation offers a therapeutic option. A case is described of recurrence of Langerhans' cell histiocytosis which was associated with deterioration in lung function
four years following bilateral lung transplantation. Patients
transplanted for Langerhans' cell histiocytosis should be followed up
with this complication in mind.
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