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Thorax 2000;55:962-963 ( November )

Short paper

Resource implications of patients with multidrug resistant tuberculosis V L C White, J Moore-Gillon

Department of Respiratory Medicine, Bart's and the London NHS Trust, St Bartholomew's Hospital, London EC1A 7BE, UK

Correspondence to: Dr V L C White vlcw{at}btinternet.com

Received 5 January 2000; Returned to authors 29 March 2000; Revised version received 30 June 2000; Accepted for publication 28 July 2000

BACKGROUND---Multidrug resistant tuberculosis (MDR TB) requires a complex drug regimen and lengthy multidisciplinary care. The financial cost of successful management of each case is potentially large.
METHODS---The costs of managing nine HIV negative patients with pulmonary MDR TB were compared with 18 age group and ethnicity matched controls with fully sensitive disease. Calculations included: cost of outpatient visits and inpatient stays including negative pressure isolation; costs of drug provision and toxicity monitoring; costs of additional procedures and multidisciplinary referrals.
RESULTS---The mean cost of managing a case of pulmonary MDR TB was in excess of £60 000 and for sensitive disease it was £6040.
CONCLUSIONS---Clinicians and healthcare commissioning authorities may both be underestimating the costs of managing MDR TB, and accordingly the consequences for units dealing with such cases may be serious. Funding of care for MDR TB in the UK requires strategic decisions at regional or governmental level.


Keywords: tuberculosis; multidrug resistance; healthcare resources


© 2000 by Thorax



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