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Department of
Respiratory Medicine, Airedale General Hospital, Keighley, West
Yorkshire BD20 6TD, UK
Correspondence to: Dr H S R Hosker, Department of Respiratory Medicine, Airedale General Hospital, Keighley, West Yorkshire BD20 6TD, UK
Received 12 August 1999; Returned to authors 15 October 1999; Revised version received 10 December 1999; Accepted for publication 6 January 2000
Churg-Strauss syndrome is a rare form of eosinophilic
vasculitis associated with asthma. There have been several recent case reports of the condition in association with leukotriene antagonists and it has been speculated that the Churg-Strauss syndrome was unmasked
when oral corticosteroids were withdrawn. We report a case of
Churg-Strauss syndrome associated with montelukast therapy in an
asthmatic patient in whom there had been no recent oral corticosteroid
use. We believe that this is the first such reported case and would
suggest that clinicians need to be vigilant in all patients who develop
systemic symptoms when starting treatment with leukotriene antagonists.
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