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| The first 150 words of the full text of this article appear below. |
Major technical and pharmacological advances mean that lung transplantation now offers a realistic opportunity for long term survival in selected patients with end stage pulmonary disease.1 2 Unfortunately up to 50% of patients identified as suitable candidates to undergo lung transplantation will die from their underlying lung disease before an organ becomes available.3 4 The severe shortage of donor lungs is now the major limitation to the use of the procedure as a widely available therapeutic option. The current method of donor lung evaluation excludes the vast majority of potential lung donors. New objective indices of donor lung injury may help to rationalise the selection process. This would enable many of the previously excluded organs to be accepted, addressing the current problem of organ shortage.
Donor lungs originate from ventilated brain dead patients whose
relatives have given consent for organ donation. Multiple strategies
have been adopted by the transplant community to increase
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