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Thorax 1998;53:302-307 ( April )

Review series

Lung infections bullet  4

Pathogenesis of lower respiratory tract infections due to Chlamydia, Mycoplasma, Legionella and viruses

Paul Andersen

Department of Infectious Diseases, Marselisborg Hospital, DK-8000 Århus C, Denmark

The first 150 words of the full text of this article appear below.

    Introduction

Acute infection of the lower respiratory tract comprises bronchitis, bronchiolitis, and pneumonia. From a clinical point of view it may be difficult to distinguish these disease entities and one infection may progress into another. The most common pathogens causing these infections are the primary respiratory viruses (respiratory syncytial virus (RSV), influenza virus, adenoviruses, parainfluenza virus, and rhinovirus1 2), Mycoplasma pneumoniae,3 and Chlamydia species.4-6 Legionella may cause pneumonia and non-pneumonic upper respiratory tract infection and approximately 85% of c ases are caused by L pneumophila. Long lasting sequelae such as bronchiectasis, lung fibrosis, and decreased lung function are seen after lower respiratory tract infections7-10 and it has been debated whether respiratory tract infection can cause chronic bronchial asthma.6 11-13


    Acute bronchitis and bronchiolitis

Acute bronchitis is an inflammatory condition of the bronchi often caused by infectious agents, although in many cases no aetiology can be established.14 15 It shares many pathological and clinical features with . . . [Full text of this article]




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