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Thorax 1998;53:308-314 ( April )

Occasional review

High resolution computed tomography in asthma

Alan N Mclean,a Michael W Sproule,b Michael D Cowan,b Neil C Thomsona

a Department of Respiratory Medicine, b Department of Radiology, c West Glasgow Hospitals University NHS Trust, Glasgow G12 0YN, UK

Correspondence to: Dr A N Mclean.

Received 12 August 1997; Accepted for publication 23 December 1997

The first 150 words of the full text of this article appear below.

    Introduction

The plain chest radiograph, although useful in the assessment of acute asthma, mainly to exclude unsuspected pneumothorax, collapse or consolidation,1 2 is unable to demonstrate more subtle changes within the lungs of asthmatic patients. The ability of high resolution computed tomography (HRCT), with a theoretical resolution of 100 µm, to examine small structures within the chest is now being exploited in the investigation of asthma. Recent studies have focused on the visualisation of acute airway responses to bronchoconstrictor and bronchodilator stimuli as well as airway and lung parenchymal changes in chronic asthma.


    Measurement techniques using HRCT

High resolution computed tomography has evolved from a combination of improvements in scanner hardware and the software used to reconstruct the images. The single most important feature in improving the spatial resolution is the slice thickness or collimation. In practice this is usually 1-1.5 mm. The second important feature of HRCT is to reconstruct the image using a high spatial frequency . . . [Full text of this article]




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