Patients with cystic fibrosis present a continuum of complex medical problems to their carers. It is for this reason that cystic fibrosis care is best delivered by a multidisciplinary team from recognised paediatric and adult cystic fibrosis centres. The consequences of this practice are that, over time, patients are better nourished with a slow decline in respiratory function.¹ The ultimate benefit of better care is increased survival.² Despite this greater knowledge and better management, cystic fibrosis as a disease repeatedly produces unpleasant novel management problems; the recent descriptions of a six fold increase in the incidence of digestive tract cancer and the remarkably high prevalence of osteoporosis are typical examples of the cystic fibrosis Pandora's box.^3 4

The current stigma of acquiring Burkholderia cepacia are both medical and social. The medical consequences of acquiring B cepacia may be accelerated lung disease, more intense treatment requirements, and doubt about suitability for transplantation . . . [Full text of this article]