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Department
of Intensive Care, Erasme University Hospital, Free University of
Brussels, B-1070 Belgium
Correspondence to: Professor J-L Vincent.
Received 13 August 1998; Returned to author 6 October 1998; Revised version received 26 November 1998; Accepted for publication 6 January 1999
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Introduction |
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The term "nosocomial pneumonia" broadly covers all
infections occurring 48 hours or more after hospital admission
excluding any infection incubating at the time of admission, and has
also been called hospital acquired pneumonia. Intensive care unit (ICU) acquired pneumonia (occurring within 48 hours of admission to the ICU)
and ventilator associated pneumonia (occurring within 48 hours of
starting mechanical ventilation) are also included in the broader term
"nosocomial pneumonia". The development of nosocomial pneumonia
remains a major problem in the ICU with most studies reporting an
incidence of between 9% and 45%,1-19 depending on the
groups of patients being studied, the definition of nosocomial pneumonia, and the criteria used to diagnose it. It has been shown that
nosocomial pneumonia acquired in the ICU markedly increases the length
of hospital stay12 16 20 21 and the costs of hospital care.21 22 Mortality rates may also be
increased,3 5 7 16 17 19 23 although it is not
entirely clear whether all deaths from nosocomial
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