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Thorax 2000;55:964-969 ( November )

Review series


Paediatric origins of adult lung diseases bullet  3

The genesis of adult sleep apnoea in childhood

F McNamara, C E Sullivan

David Read Laboratory, Department of Medicine, University of Sydney, NSW 2006, Australia

Correspondence to: Professor C E Sullivan ces@med.usyd.edu.au

The first 150 words of the full text of this article appear below.

    Introduction

Obstructive sleep apnoea (OSA) and central sleep apnoea have been identified and described in adults, children, and infants.1-3 It is not certain, however, if the adult sleep apnoea syndromes, particularly OSA, originate from childhood or whether paediatric and adult sleep apnoea are separate syndromes. Some investigators have suggested that the pathophysiology, criteria for diagnosis, and the management of paediatric patients with OSA are different from that for adults.4-7 Other investigators have found that risk factors, clinical symptoms, and the consequences of OSA share common features between adults, children and infants.8-11 We propose that the adult sleep apnoea syndrome is related to sleep apnoea in children, and that adult patients with sleep apnoea have been predisposed to developing apnoea since early infancy. The differences in OSA in patient populations of different age groups may represent different stages in the development of the adult form of OSA. This review will discuss the . . . [Full text of this article]




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