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8
Service de
Pneumologie, Hôpital Louis Pradel, Université Claude Bernard, 69394 Lyon Cedex, France
Correspondence to: Professor J-F Cordier
| The first 150 words of the full text of this article appear below. |
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Introduction |
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Organising pneumonia is defined pathologically by the presence
in the distal air spaces of buds of granulation tissue progressing from
fibrin exudates to loose collagen containing fibroblasts (fig
1).1 2 The lesions occur predominantly within the
alveolar spaces but are often associated with buds of granulation
tissue occupying the bronchiolar lumen (bronchiolitis obliterans). This pathological pattern is not specific for any disorder or cause, but
reflects one type of inflammatory process resulting from lung injury.
It may also be a feature of the organising stage of adult respiratory
distress syndrome and may be an accessory finding in other inflammatory
disorders such as vasculitis. However, organising pneumonia is the
particular pathological hallmark of a characteristic clinicoradiological entity called cryptogenic organising pneumonia. This terminology is preferred to the other name used for this condition
namely, idiopathic bronchiolitis obliterans with organising pneumonia (BOOP)which may be confused with other types of bronchiolar disorders,
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