| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS | REGISTER |
|
|
|
|
|||||||||||||
|
|
|||||||||||||||
1
Department of
Respiratory Medicine, Princess Margaret Hospital for Children and TVW
Institute for Child Health Research, Perth, Western Australia
Correspondence to: Dr S Stick email: stephen.stick@health.wa.gov.au
| The first 150 words of the full text of this article appear below. |
 |
Introduction |
|---|
Airway development is only one of the factors that is important
in the pathogenesis of complex respiratory disorders such as asthma and
chronic airflow limitation. For example, knowledge of the interactions
between the developing lung, genetic, environmental, and immunological
factors is essential if progress is to be made in early diagnosis and
the development of new interventions aimed at reducing the long term
morbidity from chronic lung diseases. However, such a review is beyond
the scope of this article which is limited to the role of airway
development during childhood in determining adult lung function and the
outcome of chronic airway disease. Some childhood respiratory diseases
such as cystic fibrosis and various congenital lung disorders have
obvious sequelae or adverse outcomes in adults. However, these
conditions are relatively rare compared with chronic airflow limitation
and asthma, the major symptomatic manifestations in adults of airway
abnormalities. Most studies that have examined
This article has been cited by other articles:
|
|
 |
|
  A. Kotaniemi-Syrjanen, L. P. Malmberg, A. S. Pelkonen, K. Malmstrom, and M. J. Makela Airway responsiveness: associated features in infants with recurrent respiratory symptoms Eur. Respir. J., December 1, 2007; 30(6): 1150 - 1157. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Rojas-Martinez, R. Perez-Padilla, G. Olaiz-Fernandez, L. Mendoza-Alvarado, H. Moreno-Macias, T. Fortoul, W. McDonnell, D. Loomis, and I. Romieu Lung Function Growth in Children with Long-Term Exposure to Air Pollutants in Mexico City Am. J. Respir. Crit. Care Med., August 15, 2007; 176(4): 377 - 384. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. J. L. E. Vrijlandt, J. Gerritsen, H. M. Boezen, R. G. Grevink, and E. J. Duiverman Lung Function and Exercise Capacity in Young Adults Born Prematurely Am. J. Respir. Crit. Care Med., April 15, 2006; 173(8): 890 - 896. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I A Fedorov, S J Wilson, D E Davies, and S T Holgate Epithelial stress and structural remodelling in childhood asthma Thorax, May 1, 2005; 60(5): 389 - 394. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. A. Lowe, A. Simpson, A. Woodcock, J. Morris, C. S. Murray, A. Custovic, and for the NAC Manchester Asthma and Allergy Study Gr Wheeze Phenotypes and Lung Function in Preschool Children Am. J. Respir. Crit. Care Med., February 1, 2005; 171(3): 231 - 237. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C A Edwards, L M Osman, D J Godden, D M Campbell, and J G Douglas Relationship between birth weight and adult lung function: controlling for maternal factors Thorax, December 1, 2003; 58(12): 1061 - 1065. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.T. Holgate, D. E. Davies, S. Puddicombe, A. Richter, P. Lackie, J. Lordan, and P. Howarth Mechanisms of airway epithelial damage: epithelial-mesenchymal interactions in the pathogenesis of asthma Eur. Respir. J., September 20, 2003; 22(44_suppl): 24s - 29s. [Full Text] [PDF]
|
|
|
|
|
|
T Tschernig, A S Debertin, F Paulsen, W J Kleemann, and R Pabst Dendritic cells in the mucosa of the human trachea are not regularly found in the first year of life Thorax, June 1, 2001; 56(6): 427 - 431. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS | REGISTER |
