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Thorax 2000;55:726-728 ( September )

Editorial

Hypertension in patients with sleep apnoea, a combined effect?

The first 150 words of the full text of this article appear below.

Studies in both humans and animal show beyond doubt that obstructive apnoea produces an acute rise in systemic blood pressure. Such increases are well characterised with regard to timing and peripheral events such as changes in oxyhaemoglobin saturation, pulse rate, and autonomic activity. However, following early reports of sustained hypertension in patients with sleep apnoea, it has been argued that this long term haemodynamic abnormality is related to obesity rather than to nightly repetitive apnoeas. Since obesity is so common in obstructive sleep apnoea, it is nearly impossible to accumulate chronic blood pressure data on non-obese apnoeic individuals. In the past few months, including the current issue of Thorax, four fairly definitive studies have been published. The authors of these studies conclude that there is an independent relationship between the presence of obstructive sleep apnoea and chronic hypertension, considering other risk factors including obesity.1-4

Obesity associated hypertension5 is believed . . . [Full text of this article]


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