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Institute For
Lung Health, Department of Respiratory Medicine, Glenfield Hospital,
Leicester LE3 9QP, UK
Correspondence to: Dr M D L Morgan carole.pearson@glenfield-tr.trent.nhs.uk
Received 21 August 2000; Accepted for publication 28 September 2000
| The first 150 words of the full text of this article appear below. |
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Introduction |
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The ambition of all athletes is to outperform competitors in their chosen discipline. To this end, ever more sophisticated training schedules are used to maximise physical performance. In recent years some sportsmen and women have resorted to illegal pharmacological methods to augment their training programmes and so gain an unfair advantage over their rivals.
Patients with chronic obstructive pulmonary disease (COPD) are disabled
by their inability to carry out many activities of daily living because
of exercise intolerance. This leads to increasing social isolation,
depression, and dependence. Improving physical performance is therefore
an important therapeutic goal in these patients. It has been thought
that exercise limitation in COPD was simply due to a limit to pulmonary
ventilation. However, a number of observations have indicated that this
is not true for many COPD sufferers. Firstly, the relationship between
exercise capacity and lung function impairment is poor1 2
and bronchodilator therapy often fails
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